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Fig. 6 | Laboratory Animal Research

Fig. 6

From: Hypoxia-inducible factor-1α-deficient adipose-tissue macrophages produce the heat to mediate lipolysis of white adipose tissue through uncoupling protein-1

Fig. 6

Increased UCP1-expressing macrophages in the lean individuals. A Immunohistochemistry staining of CD68 (upper) and UCP1 (lower) of omental WAT in human subjects. Red arrowheads indicate CD68- (upper) or UCP1-positive (lower) staining. Scale bar denotes 100 μm. Quantification of CD68+ cells normalized to the number of adipocytes per HPF (B) and CD68+UCP1+ cells among the total CD68+ cells (C) in patients with the body mass index (BMI) < 25 (n = 34) and BMI ≥ 25 (n = 17). Symbols and error bars in B and C are determined with the mean ± S.E.M. * and *** indicate P < 0.05 and 0.001, respectively, by Student’s t-test. D Correlation analysis between the percentage of CD68+UCP1+ cells and BMI of the human subjects

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Laboratory Animal Research

ISSN: 2233-7660