Fig. 5

GCG-RA treatment effect on EE and RER Sub-study 3: Evaluation of a GCG-RA on EE and RER compared to vehicle. A + C: Mean value EE and RER visualized during the relevant measurement period. B + D: Calculated mean ± SEM and individual values for EE and RER per treatment in the period analyzed. The treatment effect is analyzed using a paired t-test. Significant treatment comparisons are reported as *p < 0.05; **p < 0.01. EE energy expenditure, RER respiratory exchange ratio, HFD high-fat diet