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Table 4 Effects of Spirulina platensis powder on hematological parameters

From: Evaluation of the protective effects of Spirulina platensis against cyclophosphamide-induced genotoxicity

 

NC

PC

SP 37.5

SP 75

SP 150

RBC(10− 6 /μL)

7.14 ± 0.02

6.14 ± 0.04#

7.16 ± 0.25*

8.04 ± 0.17**

8.19 ± 0.04****

HL (g/dL)

14.76 ± 0.24

13.44 ± 0.25

14.74 ± 0.18

15.78 ± 0.24**

15.50 ± 0.17**

Hte (%)

43.46 ± 2.42

38.06 ± 0.56

44.82 ± 1.95*

45.94 ± 1.15**

45.94 ± 1.15**

MGV (fl.)

64.34 ± 1.66

62.28 ± 1.11

61.78 ± 1.14

60.59 ± 1.12

61.09 ± 2.13

MCHR (pg)

21.02 ± 0.36

22.36 ± 0.39

20.34 ± 0.52

19.70 ± 0.32

19.38 ± 0.32

MCHC(g/dL)

32.94 ± 1.16

36.00 ± 0.87

33.00 ± 0.99

33.32 ± 0.96

31.90 ± 1.36

WBC(103/mL)

2.62 ± 0.04

1.28 ± 0.09##

1.42 ± 0.16

1.64 ± 0.14

1.61 ± 1.36

PLT(103/μL)

513.80 ± 59.76

185.40 ± 12.26#

339.80 ± 34.52***

489.60 ± 25.76***

596.60 ± 50.40***

  1. WBC: white blood cells; HL: hemoglobin level; Hte: hematocrit; MGV: mean globular volume; MCHR: mean corpuscular hemoglobin level; MCHC: mean corpuscular hemoglobin concentration; RBC: red blood cell; PLT: platelet. The results were analyzed with one-way ANOVA, and the data are presented as the means ± SEM. # p < 0.05 ##p<0.01 (compared with the normal control); *p < 0.05 (compared with the positive control). **p<0.01 (compared with the positive control); ***p<0.001 (compared with the positive control); ****p<0.0001 (compared with the positive control). NC: normal control; PC: positive control; SP 37.5: mice treated with 37.5 mg/kg Spirulina powder; SP 75: mice treated with 75 mg/kg Spirulina powder; SP150: mice treated with 150 mg/kg Spirulina powder. WBC: white blood cells; HL: hemoglobin level; Hte: hematocrit; MGV: mean globular volume; MCHR: mean corpuscular hemoglobin level; MCHC: mean corpuscular hemoglobin concentration; RBC: red blood cell; PLT: platelet. ANOVA followed by Bonferroni correction was used to measure significant differences between groups with a significance level of <0.05. # p < 0.05 ##p<0.01 (compared to the normal control); *p < 0.05 (compared to the positive control). **p<0.01 (compared with the positive control); ***p<0.001 (compared to the positive control); ****p<0.0001 (compared to the positive control)